Molecular Formula | C17H14Cl2N6O |
Molar Mass | 389.24 |
Density | 1.517±0.06 g/cm3(Predicted) |
Solubility | ( < 1 mg/ml refers to the product slightly soluble or insoluble) |
pKa | 10.48±0.70(Predicted) |
Storage Condition | -20℃ |
Use | RO495 is a potent inhibitor of TYK2 with IC50 of 1.5nM on TYK2 as tested in cell-based pharmacological assays。 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.569 ml | 12.846 ml | 25.691 ml |
5 mM | 0.514 ml | 2.569 ml | 5.138 ml |
10 mM | 0.257 ml | 1.285 ml | 2.569 ml |
5 mM | 0.051 ml | 0.257 ml | 0.514 ml |
biological activity | RO495 (CS-2667) is an effective inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2). |
target | TargetValue TYK2 () |
Target | Value |